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“I am certain that the LSD experience has helped me very much.”

66 years ago, the founder of Alcoholics Anonymous tried LSD — and ignited a controversy still raging today

ByKatie MacBride
Don't trip

LSD-like drug may treat depression without the "trip" effect — mouse study

If human trials go well, the drug could revolutionize psychiatric pharmacology.

ByKatie MacBride
A Trip Begins

Scientists uncover the molecular origins of an LSD trip

"Now we know how psychedelic drugs work – finally!"

ByEmma Betuel
Blotter blog

Can LSD help struggling people make friends? Why a new study is so promising

BySarah Sloat
Mind and Body

Study: A microdose of LSD could alter a fundamental human experience

"Anyone on any of these doses could sit behind a computer and do their work."

ByEmma Betuel
Mental Health

LSD and Magic Mushrooms Dramatically Rewire the Brain, New Study Reveals

This finding could usher in a new type of antidepressant and expand psychedelic-assisted therapy.

ByMiriam Fauzia
Brain Buzz

Here's how 4 hallucinogenic drugs transform your brain

Here's what's happening in your brain when you take LSD, MDMA, magic mushrooms, and ketamine.

ByKatie MacBride
LSDownward dog

Why LSD may be as good for you as yoga

Journey to the center of your mindfulness.

ByVince Polito and Stephen Bright
Trippy

Psychedelic study reveals how LSD changes the brain

"Now we know how psychedelic drugs work — finally!"

ByGrace Browne
Trippy

How LSD binds to your brain cells

ByJoAnna Wendel
Trippy

Can you overdose on LSD? What 3 case studies teach us

“The evidence is: Any drug can be used and any drug can be abused."

ByAli Pattillo
Mind and Body

Study reveals what happens to the brain on LSD

The psychedelic experience has a lot in common with sensory overload.

ByClaire Cameron
Health

Psychedelics' Role in Beating Alcoholism Illustrated in LSD, Psilocybin Study

"There's incredible potential here."

BySarah Sloat
Health

LSD-Tripping Brains Reveal How the Drug Causes the Psychedelic Experience

This is your brain on sensory overload.

ByYasmin Tayag
Health

Microdosing LSD May Make You Wiser and More Creative, Study Reveals

But it's still totally illegal.

ByThomas Anderson and Rotem Petranker
Science

Why LSD and MDMA Drugs Are Making a Comeback for Science

It's a psychedelic renaissance.

ByErika Dyck
Health

Psychedelic Drugs Reshape Cells to "Repair" Neurons in Our Brains

Psychedelics could show the way to a new generation of medicine.

ByPeter Hess
Science

LSD Gives Congenitally Blind Man Synesthesia-Like Hallucinations

'Every time I did acid, I experienced something new and spectacular.'

BySarah Sloat
Science

LSD Blurs the Barrier Between You and Everyone Else, New Study Finds

There's a reason acid trips create feeling of "oneness."

BySarah Sloat
Science

LSD Study Reveals Unprecedented "Harmonic" Reorganization of Brain

The drug appears to hit a "reset" button in the brain.

ByPeter Hess
Health

These Troops Were Ordered to Take LSD

"Sir, YES, Sir!"

ByInverse Video
Culture

Happy 79th Birthday, LSD!

Albert Hoffman first synthesized the chemical on November 16, 1938.

ByPeter Hess
Science

Microdosing LSD Is Safer Than Taking Antidepressants, Says Neurobiologist

The latest trend in self-medication might be legally risky but biologically tame.

ByJacqueline Ronson
Health

The Plan to Prove Microdosing Makes You Smarter

Amanda Feilding has been working towards this goal for half a century.

ByJacqueline Ronson
Science

Microdosing LSD Is Still Just Informed Guesswork

ByJacqueline Ronson
Science

100 Therapeutic LSD Trips Helped Cary Grant Prepare for the Future

BySarah Sloat
Science

Crowdfunders Greenlight World's First LSD Microdosing Study

ByYasmin Tayag
Science

Shrooms vs. Acid: The Scientific Difference Between LSD and Magic Mushrooms

Two hallucinogens, both alike in trippiness.

BySarah Sloat
Health

On "Bicycle Day," Albert Hofmann Took the First LSD Trip

A scientist's brave self-experimentation led to a new awakening.

ByYasmin Tayag
Science

The Man Who Made it Rain Orange Sunshine

Tim Scully was a revolutionary psychonaut and remains a very nice dude.

BySarah Sloat