In the 1950s and 1960s, psychedelics showed promise as treatments for conditions like alcoholism, but the criminalization of psilocybin (the psychoactive substance in magic mushrooms) and LSD put research on hold.
In recent years, calls for formal research to explore whether these substances can treat brain conditions have grown — and researchers are answering the calls.
Six months later, about 80 percent of the participants reported fewer symptoms of depression than before the treatment. Some even reported that they no longer feared death.
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All the participants reported feelings of hopelessness, helplessness, and a lack of meaning or purpose, collectively categorized as “demoralization.”
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All participants saw some reduction in their OCD symptoms during at least one of the testing sessions, which lasted more than 24 hours.
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Participants also underwent a 4-week period of cognitive-behavioral therapy while still using cigarettes. But six months after both treatments, 80 percent of participants remained abstinent from cigarettes.